Breast Cancer - Moose and Doc

A breast cancer explanations website

 

May 7, 2019 By Dr. Halls

This page is a continuation of the list of types of breast cancer. Return to page 1 of the breast cancer types list.

 

Benign Proliferative Breast Lesions and Adenomas

Neoplastic cell growth is always a concern for potential breast cancer. While it is true that sometimes breast cancers can develop from epithelial breast neoplasms, most of the time this does not occur. If there is nothing ‘atypical’ about the cells or the lesion itself, then the lesion is most likely one of a number of benign epithelial breast changes. If benign epithelial cell breast changes results in a tumor formation, it is often described as an ‘adenoma’, and if the growth is confined to the breast lobules it might be referred to as an ‘adenosis’.

  1. Florid Hyperplasia of the breast.
  2. Apocrine metaplasia of the breast.
  3. Clear Cell breast Metaplasia
  4. Breast Adenoma
  5. Tubular Adenoma of the breast.
  6. Squamous Cell Metaplasia of the breast.
  7. Lactating adenoma
  8. Apocrine breast adenoma
  9. Nipple adenoma
  10. Pleomorphic breast adenoma
  11. Cystic adenoma of the breast
  12. Breast fibroadenoma
  13. Hamartoma of the breast.
  14. Breast fibroadenolipoma
  15. Sclerosing adenosis of the breast
  16. Sclerotic breast stroma, breast sclerosis
  17. Radial Scar

Soft Tissue (mesenchymal) breast tumors

Unlike breast carcinomas, which originate in epithelial cells, there are also breast tumors which develop out of breast ‘soft tissue’ cells. The majority of soft tissue breast tumors are usually benign but can be malignant. Until they are properly diagnosed they may give an appearance of a conventional breast cancer tumor. Mesenchymal cells are immature ‘stem cells’, which can differentiate into a variety of cell types, including connective tissues (sometimes called ‘stromal cells’ as they form ‘supportive structures’, and muscle tissues.

Primarily fibrous soft tissue breast tumors

  1. Leiomyosarcoma of the breast
  2. Breast angiosarcoma
  3. Spindle Cell breast Lipoma

Primarily stromal soft tissue breast tumors

  1. Breast Myofibroblastoma
  2. Inflammatory myofibroblastic tumor of the breast
  3. Solitary fibrous tumor of the breast
  4. Breast leiomyoma
  5. Nodular fasciitis of the breast
  6. Fibromatosis of the breast
  7. Diabetic Fibrous Mastopathy of the breast
  8. Hemangiopericytoma of the breast
  9. Pseudoangiomatous Stromal Hyperplasia of the breast. ( PASH)
  10. Vascular Breast Tumors, angiolipoma, hemangioma
  11. Breast Schwannoma
  12. Breast Neurofibroma
  13. Granular Cell Tumor of the breast

Myoepithelial Breast Lesions

Some hyperplastic breast lesions are composed of cells which show both myoepithelial and epithelial characteristics. Myoepithelial cells are usually located in a thin layer just above the basement membrane in glandular epithelium. They are commonly found in the sweat glands, salivary glands, and also the mammary glands. Myoepithelial cells are very important for the body’s ‘wound healing’ process, and generally speaking when myoepithelial cells are found in a breat neoplasm, the tumor tends to be benign. However, myoepithelial cells can also become malignant, though rarely, and myoepithelial breast tumor will usually exhibit a certain percentage of malignant myoepithelial cells alongside malignant epithelial cells.

  1. Myoepithelioma of the breast.
  2. Breast adenomyoepithelioma

This link goes to the old index, but the new content listed on the homepage is better.

About Steven Halls

Dr Halls has 25 years experience as a radiologist. He worked for 13 years at Cross Cancer Institute in Edmonton, a world-class cancer treatment facility. He has had high-volume experience with cancer, interventional procedures, clinical trials and his own phase 1 and 2 research in MRI and breast cancer staging.

 

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